Many serious or life-threatening diseases have already been treated with cord blood. The following is a list of diseases that have been treated with cord blood and other sources of the same type of stem cell, like bone marrow
Leukemias, Lymphomas and Other Blood Cancers
- Acute Biphenotypic Leukemia
- Acute Lymphocytic Leukemia (ALL)
- Acute Myelogenous Leukemia (AML)
- Acute Undifferentiated Leukemia
- Adult T Cell Leukemia/Lymphoma
- Chronic Lymphocytic Leukemia (CLL)
- Chronic Myelogenous Leukemia (CML)
- Hodgkin’s Lymphoma
- Juvenile Chronic Myelogenous Leukemia (JCML)
- Juvenile Myelomonocytic Leukemia (JMML)
- Multiple Myeloma
- Myeloid/Natural Killer (NK)
- Cell Precursor Acute Leukemia
- Non-Hodgkin’s Lymphoma
- Prolymphocytic Leukemia
- Plasma Cell Leukemia
- Waldenstrom’s Macroglobulinemia
|
Other Cancers
- Brain Tumors†
- Ewing Sarcoma
- Neuroblastoma
- Ovarian Cancer†
- Renal Cell Carcinoma†
- Rhabdomyosarcoma
- Small-Cell Lung Cancer†
- Testicular Cancer†
- Thymoma (Thymic Carcinoma)
|
Histiocytic Disorders
- Hemophagocytic Lymphohistiocytosis (HLH)
- Hemophagocytosis
- Langerhans?Cell Histiocytosis (Histiocytosis X)
|
Hemoglobinopathies
- Beta Thalassemia Major
- Sickle Cell Disease
|
Bone Marrow Failure Disorders
- Aplastic Anemia (Severe)
- Blackfan-Diamond Anemia
- Congenital Amegakaryocytic Thrombocytopenia (CAT)
- Congenital Cytopenia
- Congenital Dyserythropoietic Anemia
- Dyskeratosis Congenita
- Fanconi Anemia
- Paroxysmal Nocturnal Hemoglobinuria (PNH)
- Pure Red Cell Aplasia
|
Myelodysplastic/Myeloproliferative Disorders
- Acute Myelofibrosis
- Agnogenic Myeloid Metaplasia (Myelofibrosis)
- Amyloidosis
- Chronic Myelomonocytic Leukemia (CMML)
- Essential Thrombocythemia
- Polycythemia Vera
- Refractory Anemias (RA) including:
- Refractory Anemia with Excess Blasts (RAEB)
- Refractory Anemia with Excess Blasts in Transition (RAEB-T)
- Refractory Anemia with Ringed Sideroblasts (RARS
|
Inherited Metabolic Disorders
- Fucosidosis
- Gaucher Disease
- Hunter Syndrome (MPS-II)
- Hurler Syndrome (MPS-IH)
- Krabbe Disease
- Lesch-Nyhan Syndrome
- Mannosidosis
- Maroteaux-Lamy Syndrome (MPS-VI)
- Metachromatic Leukodystrophy
- Mucolipidosis II (I-cell Disease)
- Neuronal Ceroid Lipofuscinosis (Batten Disease)
- Niemann-Pick Disease
- Sandhoff Disease
- Sanfilippo Syndrome (MPS-III)
- Scheie Syndrome (MPS-IS)
- Sly Syndrome (MPS-VII)
- Tay Sachs
- Wolman Disease
|
Inherited Immune System Disorders
- Chronic Granulomatous Disease
- Congenital Neutropenia
- Leukocyte Adhesion Deficiency
- Severe Combined Immunodeficiencies (SCID) including:
- Adenosine Deaminase Deficiency
- Bare Lymphocyte Syndrome
- Chediak-Higashi Syndrome
- Kostmann Syndrome
- Omenn Syndrome
- Purine Nucleoside Phosphorylase Deficiency
- Reticular Dysgenesis
- Wiskott-Aldrich Syndrome
- X-Linked Lymphoproliferative Disorder
|
Other Inherited Disorders
- Cartilage-Hair Hypoplasia
- Congenital Erythropoietic Porphyria (Gunther Disease)
- DiGeorge Syndrome
- Osteopetrosis
|
Other
- Chronic Active Epstein Barr
- Evans Syndrome
- Multiple Sclerosis†
- Rheumatoid Arthritis†
- Systemic Lupus Erythematosus†
- Thymic Dysplasia
|
Regenerative Medicine Clinical Trials†
- Neonatal Brain Injury
- Cerebral Palsy
- Type 1 Diabetes
|
|
The newborn may be able to use his or her cord blood for some of the conditions on this list, but not all. In some cases, a matched sibling’s stem cells would be the first choice. Some of the conditions on this list, including the regenerative medicine uses, are experimental and are in clinical trials.
Source: Medical literature and clinicaltrials.gov.
†Not eligible for CBR’s Designated Treatment Program.®
Source: Cord Blood Registry (USA)
