List of Standard Diseases Treatable with Stem CellsCryo-Save

Diseases Treated

List of Standard Diseases Treatable with Stem Cells
Referenced by the National Marrow Donor Program

The list includes diagnoses for which transplant is a standard treatment as well as diagnoses for which the role of transplant is a newer option¹. Essentially stem cells from all three sources (bone marrow, mobilized peripheral blood and umbilical cord blood) can and have been used to treat these groups of diseases².

Leukaemias and lymphomas Cancer of the lymphocytes, a type of blood cell that forms part of the immune system, also called “cancer of the blood”.
Acute lymphoblastic leukaemia Acute myelogenous leukaemia Chronic lymphocytic leukaemia Chronic myelogenous leukaemia Hodgkin lymphoma Non-Hodgkin lymphoma Juvenile myelomonocytic leukaemia	Hodgkin lymphoma Non-Hodgkin lymphoma Juvenile myelomonocytic leukaemia
Multiple myeloma and other plasma cell disorders Cancer of the plasma cells in the bone marrow.
Severe aplastic anaemia and other marrow failure states A group of disorders that result in the failure of normal functioning of cells in the bone marrow./td>
Amegakaryocytosis/congenital thrombocytopenia Fanconi anaemia	Paroxysmal nocturnal hemoglobinuria(PNH) Pure red cell aplasia Severe aplastic anaemia
SCID and other inherited immune system disorders Diseases in which children are born without an immune system or with an incomplete immune system.
Severe combined immunodeficiency (SCID, all sub-types)	Wiskott-Aldrich syndrome
Hemoglobinopathies Genetic defects that result in abnormal structure of one of the globin chains of the haemoglobin molecule that is responsible for carrying of oxygen in the blood.
Beta thalassemia major	Sickle cell disease
Hurler’s Syndrome and other inherited metabolic disorders A group of inherited diseases in which the lack of an enzyme affects various organs and tissues, including the brain. Enzymes are proteins that play many roles, including metabolizing (breaking down) substances in the body.
Adrenoleukodystrophy Hurler’s syndrome (MPS-IH)	Metachromatic leukodystrophy
Myelodysplastic and myeloproliferative disorders A group of diseases that affect the bone marrow and blood. It can also develop into a fast-growing, severe leukaemia called acute myelogenous leukaemia
Agnogenic myeloid metaplasia(myelofibrosis)	Chronic myelomonocytic leukaemia Refractory anaemia (all types)
Familial erythrophagocytic lymphohistiocytosis and other histiocytic disorders Diseases that occur when there is an over-production of white blood cells known as histiocytes that can lead to organ damage and tumour formation.
Other malignancies
References: National Marrow Donor Program Broxmeyer, Hal E. Enhancing engraftment of cord blood cells via insight intothe biology of stem/progenitor cell function. Annals of the New York Academy of Sciences. Issue: Hematopoietic Stem Cells VIII

Name & Surname*
Contact Number*
Email Address*
Due Date*
Hospital of Birth*
Message*
Please type the numbers you see in the image below