Cord Stem Cells 101

Cord Stem Cells 101

Cord Stem Cells 101

Rich
Source of
Stem Cells
Blue Horizonal Bar

Cord blood is a rich source of haematopoietic (blood-forming) stem cells. Cord blood transplantation has become established practice throughout the world, including in South Africa.

Flexible
Blue Horizonal Bar

Cord tissue is a source of mesenchymal stem cells, a type of stem cell which is able to replicate, regenerate and differentiate into many kinds of specialised cells in the body (including heart, muscle and nerve cells). The use of this type of stem cell, in the fields of Regenerative Medicine and Tissue Engineering, is currently being evaluated in clinical trials abroad.

Clinical
Use
Blue Horizonal Bar

Data from the USA indicate that there is a 1 in 217 probability that a person will need a stem cell transplant in their lifetime. Day-to-day, lives are being saved with cord blood stem cell transplants world-wide.*

*Reference: Patents Guide to Cord Blood Foundation

Exciting
Future
Blue Horizonal Bar

To date, more than 35,000 cord blood transplants have been performed world-wide, in the treatment of over 80 blood-related conditions. Emerging therapies for cord stem cells, currently being evaluated in clinical trials, include autism and cerebral palsy.

Rich
Source of
Stem Cells
Blue Horizonal Bar

Cord blood is a rich source of haematopoietic (blood-forming) stem cells. Cord blood transplantation has become established practice throughout the world, including in South Africa.

Flexible
Blue Horizonal Bar

Cord tissue is a source of mesenchymal stem cells, a type of stem cell which is able to replicate, regenerate and differentiate into many kinds of specialised cells in the body (including heart, muscle and nerve cells). The use of this type of stem cell, in the fields of Regenerative Medicine and Tissue Engineering, is currently being evaluated in clinical trials abroad.

Clinical
Use
Blue Horizonal Bar

Data from the USA indicate that there is a 1 in 217 probability that a person will need a stem cell transplant in their lifetime. Day-to-day, lives are being saved with cord blood stem cell transplants world-wide.*

*Reference: Patents Guide to Cord Blood Foundation

Exciting
Future
Blue Horizonal Bar

To date, more than 35,000 cord blood transplants have been performed world-wide, in the treatment of over 80 blood-related conditions. Emerging therapies for cord stem cells, currently being evaluated in clinical trials, include autism and cerebral palsy.

Rich
Source of
Stem Cells
Blue Horizonal Bar

Cord blood is a rich source of haematopoietic (blood-forming) stem cells. Cord blood transplantation has become established practice throughout the world, including in South Africa.

Flexible
Blue Horizonal Bar

Cord tissue is a source of mesenchymal stem cells, a type of stem cell which is able to replicate, regenerate and differentiate into many kinds of specialised cells in the body (including heart, muscle and nerve cells). The use of this type of stem cell, in the fields of Regenerative Medicine and Tissue Engineering, is currently being evaluated in clinical trials abroad.

Clinical
Use
Blue Horizonal Bar

Data from the USA indicate that there is a 1 in 217 probability that a person will need a stem cell transplant in their lifetime. Day-to-day, lives are being saved with cord blood stem cell transplants world-wide.*

*Reference: Patents Guide to Cord Blood Foundation

Exciting
Future
Blue Horizonal Bar

To date, more than 35,000 cord blood transplants have been performed world-wide, in the treatment of over 80 blood-related conditions. Emerging therapies for cord stem cells, currently being evaluated in clinical trials, include autism and cerebral palsy.

What are stem cells and how do they work cell image

WHAT ARE STEM CELLS
& HOW DO THEY WORK?

White Horizonal Bar

Stem cells can be thought of as basic building blocks of our body. They can replicate and renew themselves and have the potential to become almost any other type of cell in the body. Stem cells are found, for example, in bone marrow, peripheral blood and in umbilical cord blood and umbilical cord tissue as well as in many other tissues in the body. They are ‘master’ cells from which all of the various types of blood cells, as well as tissue in bone, muscle, heart, liver, kidney, skin etc., develop.

Umbilical cord blood and cord tissue is a rich source of stem cells and parents now have the opportunity to store (cryo-preserve) these stem cells at the time of birth.

What are stem cells and how do they work cell image

WHAT ARE STEM CELLS & HOW DO THEY WORK?

White Horizonal Bar

Stem cells can be thought of as basic building blocks of our body. They can replicate and renew themselves and have the potential to become almost any other type of cell in the body. Stem cells are found, for example, in bone marrow, peripheral blood and in umbilical cord blood and umbilical cord tissue as well as in many other tissues in the body. They are ‘master’ cells from which all of the various types of blood cells, as well as tissue in bone, muscle, heart, liver, kidney, skin etc., develop.

Umbilical cord blood and cord tissue is a rich source of stem cells and parents now have the opportunity to store (cryo-preserve) these stem cells at the time of birth.

What are stem cells and how do they work cell image

WHAT ARE STEM CELLS & HOW DO THEY WORK?

White Horizonal Bar

Stem cells can be thought of as basic building blocks of our body. They can replicate and renew themselves and have the potential to become almost any other type of cell in the body. Stem cells are found, for example, in bone marrow, peripheral blood and in umbilical cord blood and umbilical cord tissue as well as in many other tissues in the body. They are ‘master’ cells from which all of the various types of blood cells, as well as tissue in bone, muscle, heart, liver, kidney, skin etc., develop.

Umbilical cord blood and cord tissue is a rich source of stem cells and parents now have the opportunity to store (cryo-preserve) these stem cells at the time of birth.

About Cord Blood

About Cord Tissue

Cord blood is the blood remaining in your baby’s umbilical cord following birth. Cord blood is a rich source of haematopoietic (blood-forming) stem cells.

Cord tissue is the tissue that surrounds the umbilical vein and vessels in the umbilical cord.

Cord tissue is a source of mesenchymal stem cells, a type of stem cell which is able to replicate, regenerate and differentiate into many kinds of specialised cells in the body (including heart, muscle and nerve cells). The use of this type of stem cell, in the fields of Regenerative Medicine and Tissue Engineering, is currently being evaluates in clinical trials abroad.

About Cord Blood

Cord blood is the blood remaining in your baby’s umbilical cord following birth. Cord blood is a rich source of haematopoietic (blood-forming) stem cells.

About Cord Tissue

Cord tissue is the tissue that surrounds the umbilical vein and vessels in the umbilical cord.

Cord tissue is a source of mesenchymal stem cells, a type of stem cell which is able to replicate, regenerate and differentiate into many kinds of specialised cells in the body (including heart, muscle and nerve cells). The use of this type of stem cell, in the fields of Regenerative Medicine and Tissue Engineering, is currently being evaluates in clinical trials abroad.

Finding a match

Finding a match

Your own
stem cells

(Autologous)

100%

Stem cells from
identical twins

(Syngeneic)

100%

Stem cells from
biological parents

(Haploidentical)

50%

Stem cells
from siblings

(Allogenic)

25%

Stem cells from an
unrelated donor

(Allogenic)

0.001%

Your
own
stem
cells

(Autologous)

100%

Stem cells
from
identical
twins

(Syngeneic)

100%

Stem cells
from
biological
parents

(Haploidentical)

50%

Stem
cells
from
siblings

(Allogenic)

25%

Stem cells
from an
unrelated
donor

(Allogenic)

0.001%

Your own
stem cells

(Autologous)

100%

Stem cells from
identical twins

(Syngeneic)

100%

Stem cells from
biological parents

(Haploidentical)

50%

Stem cells
from siblings

(Allogenic)

25%

Stem cells from an
unrelated donor

(Allogenic)

0.001%

Finding a match puzzle image

Your baby's cord blood is a rich source of blood-forming stem cells

White Horizonal Bar

These stem cells would be an exact match for your child should an autologous transplant be indicated. Biological siblings have a 25% chance of being a match. Should there be a need to obtain stem cells for a transplant from an unrelated donor through a National or International Donor Registry (e.g. through the South African Bone Marrow Registry – SABMR), the likelihood of finding a match is approximately 0.001%

Finding a match puzzle image

Your baby's cord blood is a rich source of blood-forming stem cells

White Horizonal Bar

These stem cells would be an exact match for your child should an autologous transplant be indicated. Biological siblings have a 25% chance of being a match. Should there be a need to obtain stem cells for a transplant from an unrelated donor through a National or International Donor Registry (e.g. through the South African Bone Marrow Registry – SABMR), the likelihood of finding a match is approximately 0.001%

Finding a match puzzle image

Your baby's cord blood is a rich source of blood-forming stem cells

White Horizonal Bar

These stem cells would be an exact match for your child should an autologous transplant be indicated. Biological siblings have a 25% chance of being a match. Should there be a need to obtain stem cells for a transplant from an unrelated donor through a National or International Donor Registry (e.g. through the South African Bone Marrow Registry – SABMR), the likelihood of finding a match is approximately 0.001%

WHY COLLECT BOTH
CORD BLOOD &
CORD TISSUE?

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In the past, umbilical cord blood and cord tissue have been viewed as medical waste and discarded, resulting in the loss of this potential life-saving resource. More than 97% of cord blood is still disposed of after birth and lost as a potential source of stem cells should a transplant be needed. These stem cells can now be saved with CryoSave so that your child can potentially benefit from established cord blood transplant therapies, as well as new developments in cellular therapy and regenerative medicine, in his or her lifetime.

Saving both cord blood and cord tissue will provide you with two different types of stem cells (hematopoietic stem cells from cord blood and mesenchymal stem cells from cord tissue) – which means more potential treatment options for your family.

The probability that a child, or his or her sibling, will develop a disease that requires a stem cell transplant is low, however, should a a transplant be needed, cord blood stem cells stored in a family stem cell bank have certain advantages.

Advantages:

  • Cord blood can be made available for transplant in a relatively short period of time compared to other sources of stem cells; it is collected in advance, tested, cryo-preserved and stored.
  • Cord blood stem cells are more ‘naïve’ than most other sources of stem cells. Cord blood is collected at birth and exposure to harmful environmental factors is minimal at this point in time.
  • In many studies, cord blood transplants have been shown to have significantly lower rates of the transpant complication graft vs host disease (GvHD), which improves outcomes.
  • There is scope for new developments and treatment possibilities due to the naïve nature and higher proliferation capacity of cord blood stem cells. Cord blood has, for example, been shown to induce regeneration of cells in the central nervous system and published results from internationally conducted clinical trials indicate that cord blood derived stem cells may be effective in treating neurological conditions such as autism and cerebral palsy.

WHY COLLECT BOTH CORD BLOOD & CORD TISSUE?

Blue Horizonal Bar

In the past, umbilical cord blood and cord tissue have been viewed as medical waste and discarded, resulting in the loss of this potential life-saving resource. More than 97% of cord blood is still disposed of after birth and lost as a potential source of stem cells should a transplant be needed. These stem cells can now be saved with CryoSave so that your child can potentially benefit from established cord blood transplant therapies, as well as new developments in cellular therapy and regenerative medicine, in his or her lifetime.

Saving both cord blood and cord tissue will provide you with two different types of stem cells (hematopoietic stem cells from cord blood and mesenchymal stem cells from cord tissue) – which means more potential treatment options for your family.

The probability that a child, or his or her sibling, will develop a disease that requires a stem cell transplant is low, however, should a a transplant be needed, cord blood stem cells stored in a family stem cell bank have certain advantages.

Advantages:

  • Cord blood can be made available for transplant in a relatively short period of time compared to other sources of stem cells; it is collected in advance, tested, cryo-preserved and stored.
  • Cord blood stem cells are more ‘naïve’ than most other sources of stem cells. Cord blood is collected at birth and exposure to harmful environmental factors is minimal at this point in time.
  • In many studies, cord blood transplants have been shown to have significantly lower rates of the transpant complication graft vs host disease (GvHD), which improves outcomes.
  • There is scope for new developments and treatment possibilities due to the naïve nature and higher proliferation capacity of cord blood stem cells. Cord blood has, for example, been shown to induce regeneration of cells in the central nervous system and published results from internationally conducted clinical trials indicate that cord blood derived stem cells may be effective in treating neurological conditions such as autism and cerebral palsy.

WHY COLLECT BOTH CORD BLOOD & CORD TISSUE?

Blue Horizonal Bar

In the past, umbilical cord blood and cord tissue have been viewed as medical waste and discarded, resulting in the loss of this potential life-saving resource. More than 97% of cord blood is still disposed of after birth and lost as a potential source of stem cells should a transplant be needed. These stem cells can now be saved with CryoSave so that your child can potentially benefit from established cord blood transplant therapies, as well as new developments in cellular therapy and regenerative medicine, in his or her lifetime.

Saving both cord blood and cord tissue will provide you with two different types of stem cells (hematopoietic stem cells from cord blood and mesenchymal stem cells from cord tissue) – which means more potential treatment options for your family.

The probability that a child, or his or her sibling, will develop a disease that requires a stem cell transplant is low, however, should a a transplant be needed, cord blood stem cells stored in a family stem cell bank have certain advantages.

Advantages:

  • Cord blood can be made available for transplant in a relatively short period of time compared to other sources of stem cells; it is collected in advance, tested, cryo-preserved and stored.
  • Cord blood stem cells are more ‘naïve’ than most other sources of stem cells. Cord blood is collected at birth and exposure to harmful environmental factors is minimal at this point in time.
  • In many studies, cord blood transplants have been shown to have significantly lower rates of the transpant complication graft vs host disease (GvHD), which improves outcomes.
  • There is scope for new developments and treatment possibilities due to the naïve nature and higher proliferation capacity of cord blood stem cells. Cord blood has, for example, been shown to induce regeneration of cells in the central nervous system and published results from internationally conducted clinical trials indicate that cord blood derived stem cells may be effective in treating neurological conditions such as autism and cerebral palsy.

What Diseases Can Be Treated?

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Over the past 30 years, more than 35,000 cord blood transplants have been performed world-wide. These transplants have treated blood disorders such as bone marrow failure, haematological malignancies, inherited blood disorders, immuno-deficiency syndromes and metabolic disorders.

What Diseases Can Be Treated?

White Horizonal Bar

Over the past 30 years, more than 35,000 cord blood transplants have been performed world-wide. These transplants have treated blood disorders such as bone marrow failure, haematological malignancies, inherited blood disorders, immuno-deficiency syndromes and metabolic disorders.

What Diseases Can Be Treated?

White Horizonal Bar

Over the past 30 years, more than 35,000 cord blood transplants have been performed world-wide. These transplants have treated blood disorders such as bone marrow failure, haematological malignancies, inherited blood disorders, immuno-deficiency syndromes and metabolic disorders.

Umbilical Cord Blood Approved Stem Cell Therapies

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Umbilical Cord Blood Approved Stem Cell Therapies

Blue Horizonal Bar

Umbilical Cord Blood Approved Stem Cell Therapies

Blue Horizonal Bar

BLOOD CANCERS

Acute Lymphoblastic Leukaemia (ALL)
Acute Myeloid Leukaemia (AML)
Chronic Myeloid Leukaemia (CML)
Myelodysplastic Syndrome (MDS)
Multiple Myeloma
Hodgkin’s Lymphoma
Non-Hodgkin’s Lymphoma

BONE MARROW FAILURE SYNDROMES

Severe Acquired Aplastic Anaemia,
Unspecified Fanconi Anaemia

BLOOD DISORDERS

Sickle Cell Disease
Thalassemia

IMMUNODEFICIENCIES

Severe Combined Immunedeficiency (SCID)
Wiskott-Aldrich Syndrome

INHERITED METABOLIC DISORDERS

Hurler Disease (MPS type IH)
Osteopetrosis
Adrenoleukodystrophy
Krabbe Disease

OTHER

Neuroblastoma
Solid Tumours

BLOOD CANCERS

Acute Lymphoblastic Leukaemia (ALL)
Acute Myeloid Leukaemia (AML)
Chronic Myeloid Leukaemia (CML)
Myelodysplastic Syndrome (MDS)
Multiple Myeloma
Hodgkin’s Lymphoma
Non-Hodgkin’s Lymphoma

BONE MARROW FAILURE SYNDROMES

Severe Acquired Aplastic Anaemia,
Unspecified Fanconi Anaemia

BLOOD DISORDERS

Sickle Cell Disease
Thalassemia

IMMUNODEFICIENCIES

Severe Combined Immunedeficiency (SCID)
Wiskott-Aldrich Syndrome

INHERITED METABOLIC DISORDERS

Hurler Disease (MPS type IH)
Osteopetrosis
Adrenoleukodystrophy
Krabbe Disease

OTHER

Neuroblastoma
Solid Tumours

BLOOD CANCERS

Acute Lymphoblastic Leukaemia (ALL)
Acute Myeloid Leukaemia (AML)
Chronic Myeloid Leukaemia (CML)
Myelodysplastic Syndrome (MDS)
Multiple Myeloma
Hodgkin’s Lymphoma
Non-Hodgkin’s Lymphoma

BONE MARROW FAILURE SYNDROMES

Severe Acquired Aplastic Anaemia,
Unspecified Fanconi Anaemia

BLOOD DISORDERS

Sickle Cell Disease
Thalassemia

IMMUNODEFICIENCIES

Severe Combined Immunedeficiency (SCID)
Wiskott-Aldrich Syndrome

INHERITED METABOLIC DISORDERS

Hurler Disease (MPS type IH)
Osteopetrosis
Adrenoleukodystrophy
Krabbe Disease

OTHER

Neuroblastoma
Solid Tumours

References:

  • Cairo MS, Rocha V, Gluckman E, et al. Alternative allogeneic donor sources for transplantation for childhood diseases: unrelated cord blood and haploidentical family donora. Biol Blood Marrow Transplant. 2008; 14:44-53.
  • Gluckman E, Ruggeri A, Rocha V, et al. for Eurocord, Netcord, World Marrow Donor Association and National
    Marrow Donor Program. Family-directed umbilical cord blood banking. Haematolgica. 2001; 96: 1700-1707.

References:

  • Cairo MS, Rocha V, Gluckman E, et al. Alternative allogeneic donor sources for transplantation for childhood diseases: unrelated cord blood and haploidentical family donora. Biol Blood Marrow Transplant. 2008; 14:44-53.
  • Gluckman E, Ruggeri A, Rocha V, et al. for Eurocord, Netcord, World Marrow Donor Association and National
    Marrow Donor Program. Family-directed umbilical cord blood banking. Haematolgica. 2001; 96: 1700-1707.

References:

  • Cairo MS, Rocha V, Gluckman E, et al. Alternative allogeneic donor sources for transplantation for childhood diseases: unrelated cord blood and haploidentical family donora. Biol Blood Marrow Transplant. 2008; 14:44-53.
  • Gluckman E, Ruggeri A, Rocha V, et al. for Eurocord, Netcord, World Marrow Donor Association and National
    Marrow Donor Program. Family-directed umbilical cord blood banking. Haematolgica. 2001; 96: 1700-1707.

NOVEL USES OF UMBILICAL CORD BLOOD USE IN REGENERATIVE MEDICINE

Diseases being studied in clinical trials

NOVEL USES OF UMBILICAL CORD BLOOD USE IN REGENERATIVE MEDICINE

Diseases being studied in clinical trials

  • Neonatal oxygen deprivation
  • Acquired hearing loss
  • Encephalopathy (neonatal)
  • Hypoplastic left heart syndrome
  • Ischemic Stroke (pre/peri-natal)
  • Traumatic brain injury
  • Type 1 Diabetes
  • Severe Hypoxic-ischemic Encephalopathy
  • Alzheimer’s disease
  • Bronchopulmonary dysplasia
  • Cartilage repair
  • Critical limb ischemia
  • Global development delay
  • Graft versus host diseases
  • HIV
  • Fertility
  • Intraventricular haemorrhage
  • Systemic Lupus Erythematosus
  • Spinal Cord Injury
  • Infant Lung Disease
  • Acute Ischemic Stroke
  • Neurodegenerative
  • Disorders
  • Cerebral Palsy
  • Autism Spectrum Disorders
  • Preterm Neonatal Complications
  • Global Developmental Delay
  • Type I and Type II Diabetes Mellitus
  • Congenital Diaphragmatic Hernia
  • Thromboangiitis Obliterans
  • Critical Limb Ischemia
  • Traumatic Brain Injury
  • Congenital Heart Diseases
  • Hypoplastic Left Heart Syndrome
  • Idiopathic Dilated
  • Cardiomyopathy
  • Skin-Wound/Burn
  • Epidermolysis Bullosa
  • Rheumatoid Arthritis
  • Childhood Hearing Loss
  • Sweat Gland Diseases
  • Parkinson’s Disease
  • Corneal Epithelial Wounds
  • Liver Cirrhosis
  • Viral Hepatitis
  • Ulcerative Colitis / Inflammatory Bowel
  • Disease
  • Duchenne Muscular Dystrophy
  • Hydrocephalus
  • In-Utero Brain Injury / Stroke
  • Amyotropic Lateral Sclerosis
  • Glaucoma
  • Diabetic Foot Ulcers
  • Neurodegenerative disorders
  • Stroke
  • Sweat gland regeneration
  • Neonatal oxygen deprivation
  • Acquired hearing loss
  • Encephalopathy (neonatal)
  • Hypoplastic left heart syndrome
  • Ischemic Stroke (pre/peri-natal)
  • Traumatic brain injury
  • Type 1 Diabetes
  • Severe Hypoxic-ischemic Encephalopathy
  • Alzheimer’s disease
  • Bronchopulmonary dysplasia
  • Cartilage repair
  • Critical limb ischemia
  • Global development delay
  • Graft versus host diseases
  • HIV
  • Fertility
  • Intraventricular haemorrhage
  • Systemic Lupus Erythematosus
  • Spinal Cord Injury
  • Infant Lung Disease
  • Acute Ischemic Stroke
  • Neurodegenerative
  • Disorders
  • Cerebral Palsy
  • Autism Spectrum Disorders
  • Preterm Neonatal Complications
  • Global Developmental Delay
  • Type I and Type II Diabetes Mellitus
  • Congenital Diaphragmatic Hernia
  • Thromboangiitis Obliterans
  • Critical Limb Ischemia
  • Traumatic Brain Injury
  • Congenital Heart Diseases
  • Hypoplastic Left Heart Syndrome
  • Idiopathic Dilated
  • Cardiomyopathy
  • Skin-Wound/Burn
  • Epidermolysis Bullosa
  • Rheumatoid Arthritis
  • Childhood Hearing Loss
  • Sweat Gland Diseases
  • Parkinson’s Disease
  • Corneal Epithelial Wounds
  • Liver Cirrhosis
  • Viral Hepatitis
  • Ulcerative Colitis / Inflammatory Bowel
  • Disease
  • Duchenne Muscular Dystrophy
  • Hydrocephalus
  • In-Utero Brain Injury / Stroke
  • Amyotropic Lateral Sclerosis
  • Glaucoma
  • Diabetic Foot Ulcers
  • Neurodegenerative disorders
  • Stroke
  • Sweat gland regeneration
  • Neonatal oxygen deprivation
  • Acquired hearing loss
  • Encephalopathy (neonatal)
  • Hypoplastic left heart syndrome
  • Ischemic Stroke (pre/peri-natal)
  • Traumatic brain injury
  • Type 1 Diabetes
  • Severe Hypoxic-ischemic Encephalopathy
  • Alzheimer’s disease
  • Bronchopulmonary dysplasia
  • Cartilage repair
  • Critical limb ischemia
  • Global development delay
  • Graft versus host diseases
  • HIV
  • Fertility
  • Intraventricular haemorrhage
  • Systemic Lupus Erythematosus
  • Spinal Cord Injury
  • Infant Lung Disease
  • Acute Ischemic Stroke
  • Neurodegenerative
  • Disorders
  • Cerebral Palsy
  • Autism Spectrum Disorders
  • Preterm Neonatal Complications
  • Global Developmental Delay
  • Type I and Type II Diabetes Mellitus
  • Congenital Diaphragmatic Hernia
  • Thromboangiitis Obliterans
  • Critical Limb Ischemia
  • Traumatic Brain Injury
  • Congenital Heart Diseases
  • Hypoplastic Left Heart Syndrome
  • Idiopathic Dilated
  • Cardiomyopathy
  • Skin-Wound/Burn
  • Epidermolysis Bullosa
  • Rheumatoid Arthritis
  • Childhood Hearing Loss
  • Sweat Gland Diseases
  • Parkinson’s Disease
  • Corneal Epithelial Wounds
  • Liver Cirrhosis
  • Viral Hepatitis
  • Ulcerative Colitis / Inflammatory Bowel
  • Disease
  • Duchenne Muscular Dystrophy
  • Hydrocephalus
  • In-Utero Brain Injury / Stroke
  • Amyotropic Lateral Sclerosis
  • Glaucoma
  • Diabetic Foot Ulcers
  • Neurodegenerative disorders
  • Stroke
  • Sweat gland regeneration

References:

  • Cairo MS, Tarek N, Lee DA, et al. Cellular engineering and therapy in combination with cord blood allografting in pediatric recipients. Bone Marrow Transplant. 2016;51:27-33.
  • Mazonson P, Kane M, Colberg K, et al. Prevalence of medical conditions potentially amenable to cellular therapy among families privately storing umbilical cord blood. Matern Child Health J. 2016 (online).
  • https://clinicaltrials.gov

References:

  • Cairo MS, Tarek N, Lee DA, et al. Cellular engineering and therapy in combination with cord blood allografting in pediatric recipients. Bone Marrow Transplant. 2016;51:27-33.
  • Mazonson P, Kane M, Colberg K, et al. Prevalence of medical conditions potentially amenable to cellular therapy among families privately storing umbilical cord blood. Matern Child Health J. 2016 (online).
  • https://clinicaltrials.gov

References:

  • Cairo MS, Tarek N, Lee DA, et al. Cellular engineering and therapy in combination with cord blood allografting in pediatric recipients. Bone Marrow Transplant. 2016;51:27-33.
  • Mazonson P, Kane M, Colberg K, et al. Prevalence of medical conditions potentially amenable to cellular therapy among families privately storing umbilical cord blood. Matern Child Health J. 2016 (online).
  • https://clinicaltrials.gov
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