What is the difference between umbilical cord blood and cord tissue stem cells?

CORD BLOOD

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How is it collected

After birth the umbilical cord is clamped and cut before the baby is taken away for care. The blood is collected from the umbilical cord in a quick, painless and non-invasive procedure.
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What type of stem cells it contains

Blood stem cells/ Haematopoietic stem cells (HSCs) in umbilical cord blood are blood-forming stem cells that can differentiate into red blood cells, white blood cells and platelets.
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What is it used for

Blood-forming stem cells are used to treat bone marrow failure, blood cancer and other blood disorders.
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First used

Cord blood stem cells were 1st successfully transplanted in 1988, and now it is used to treat over 80 blood-related diseases.
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Evolving medicine

In addition to the current treatments, FDA-regulated clinical trails are underway to study ways in which cord blood stem cells can be used as treatment for:

  • cerebral palsy
  • traumatic brain injury
  • acquired hearing loss
  • juvenile diabetes

CORD TISSUE

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How is it collected

A 20-25cm segment of the umbilical cord is collected after birth.
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What type of stem cells it contains

The stem cells found in the umbilical cord tissue (Wharton’s jelly) is called mesenchymal stem cells (MSC).  The umbilical cord vein and arteries contain endothelial stem cells and the umbilical cord lining contains both mesenchymal stem cells and epithelial stem cells.
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What is it used for

MSCs are able to differentiate into cartilage cells, muscle cells, bone cells, nerve cells, etc. Future treatments may include Alzheimer’s, liver and heart failure, bone regeneration, HIV, Type 1 diabetes, and more.
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First used

Clinical trials using MSCs started in 1995, with more than 200 trials currently underway.
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Evolving medicine

Cord tissue MSC are being evaluated in laboratory studies and clinical trials to treat:

  • heart disease
  • spinal cord injury
  • cartilage injury
  • liver disease