Leukemia and lymphomas
Cancer of the lymphocytes, a type of blood cell that forms part of the immune system, also called “cancer of the blood”
- Acute lymphoblastic leukaemia
- Acute myelogenous leukaemia
- Chronic lymphocytic leukaemia
- Chronic myelogenous leukaemia
- Hodgkin lymphoma
- Non-Hodgkin lymphoma
- Juvenile myelomonocytic leukaemia
Multiple myeloma and other plasma cell disorders
Cancer of the plasma cells in the bone marrow.
Severe aplastic anaemia and other marrow failure states
A group of disorders that result in the failure of normal functioning of cells in the bone marrow.
- Amegakaryocytosis/congenital thrombocytopenia
- Fanconi anaemia
- Paroxysmal nocturnal hemoglobinuria(PNH)
- Pure red cell aplasia
- Severe aplastic anaemia
SCID and other inherited immune system disorders
Diseases in which children are born without an immune system or with an incomplete immune system.
- Severe combined immunodeficiency (SCID, all sub-types)
- Wiskott-Aldrich syndrome
Genetic defects that result in abnormal structure of one of the globin chains of the haemoglobin molecule that is responsible for carrying of oxygen in the blood.
- Beta thalassemia major
- Sickle cell disease
Hurler’s Syndrome and other inherited metabolic disorders
A group of inherited diseases in which the lack of an enzyme affects various organs and tissues, including the brain. Enzymes are proteins that play many roles, including metabolizing (breaking down) substances in the body.
- Hurler’s syndrome (MPS-IH)
- Metachromatic leukodystrophy
Myelodysplastic and myeloproliferative disorders
A group of diseases that affect the bone marrow and blood. It can also develop into a fast-growing, severe leukaemia called acute myelogenous leukaemia.
- Agnogenic myeloid metaplasia (myelofibrosis)
- Chronic myelomonocytic leukaemia
- Refractory anaemia (all types)
Familial erythrophagocytic lymphohistiocytosis and other histiocytic disorders
Diseases that occur when there is an over-production of white blood cells known as histiocytes that can lead to organ damage and tumor formation.