What have stem cells done so far?

Stem cell therapies, bioprinting and other technologies are transforming the future of healthcare

Replace dead or diseased cells

  • Stem cells are used to replace dead or diseased cells e.g. blood stem cell transplant.

Regenerate tissue and organs

  • Stem cells are used in clinical trials to regenerate tissues and organs.

Bioprint tissues or organs

  • Stem cells are being used to 3D print tissues and organs.

Enhance the body’s regenerative potential

  • Scientists are studying ways to use the body’s intrinsic regenerative ability to initiate and enhance repair.

What will future results be for cord blood and tissue stem cell therapy?

As medical science continues its research into stem cells and their flexibility, the list of possible treatments grows. Recent research into the stem cells found in cord tissue has shown potential in regenerative medicine. These cells, also known as mesenchymal stem cells (MSC), can transform into many types of cells and tissues, including organs, muscles, skin and bone. Trials are underway that look into using stem cell therapies with MSC to potentially treat autism, cerebral palsy, diabetes, spinal injuries and many others. For up to date information about new developments in stem cell research, visit www.ecsbio.com

Diseases currently treatable and therapies in clinical trials

Diseases Currently Treatable
(Most common)

BLOOD CANCERS

  • Acute Lymphoblastic Leukaemia (ALL)
  • Acute Myeloid Leukaemia (AML)
  • Chronic Myeloid Leukaemia (CML)
  • Myelodysplastic Syndrome (MDS)
  • Multiple Myeloma
  • Hodgkin’s Lymphoma
  • Non-Hodgkin’s Lymphoma
  • Bone marrow failure syndromes
  • Severe Aplastic Anaemia, Unspecified
  • Fanconi Anaemia

BLOOD DISORDERS

  • Sickle Cell Disease
  • Thalassemia

IMMUNODEFICIENCIES

  • Severe Combined Immune
  • Deficiency (SCID)
  • Wiskott-Aldrich Syndrome

INHERITED METABOLIC DISORDERS

  • Hurler Disease (MPS type IH)
  • Osteopetrosis
  • Adrenoleukodystrophy
  • Krabbe Disease

AUTOIMMUNE DISEASES

  • Systemic Lupus (SLE)

Therapies in Clinical Trials
with cord blood

NEUROLOGIC DISORDER

  • Autism (Phase 2)
  • Cerebral Palsy (Phase 2)
  • Hearing Loss (acquired sensori-neural) (Phase 2)
  • Hypoxic Ischemic Encephalopathy (HIE) (Phase 1)
  • Spinal Cord Injury (Phase 2)

AUTO-IMMUNE DISORDERS

  • Crohn’s Disease (Phase 3)
  • Diabetes, Type 1 (Phase 2)
  • Graft-versus-Host Disease (GvHD) (Phase 3)
  • Kidney plus stem cell transplant (Phase 2)
  • Systemic Lupus (SLE) (Phase 2)
  • Multiple Sclerosis (Phase 1)
  • Rheumatoid Arthritis (Phase 2)
  • Scleroderma (Phase 2)

CARDIOVASCULAR

  • Critical Limb Ischemia (Phase 3)
  • Ischemic Stroke (Phase 2 placenta) (Phase 3)
  • Myocardial Infarction (Phase 3)
  • Cardiomyopathy (Phase 3)

Reference:

National Cord Blood Program, http://www.nationalcordbloodprogram.org/patients/ncbp_diseases.pdf
https://parentsguidecordblood.org/en/diseases#standard